In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with Human Carbonic Anhydrase IX and XII Inhibition

• প্রধান লেখক: Giosuè Costa (লেখক), Annalisa Maruca (লেখক), Roberta Rocca (লেখক), Francesca Alessandra Ambrosio (লেখক), Emanuela Berrino (লেখক), Fabrizio Carta (লেখক), Francesco Mesiti (লেখক), Alessandro Salatino (লেখক), Delia Lanzillotta (লেখক), Francesco Trapasso (লেখক), Anna Artese (লেখক), Stefano Alcaro (লেখক), Claudiu T. Supuran (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2020-08-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The tumor-associated isoenzymes <i>h</i>CA IX and <i>h</i>CA XII catalyze the hydration of carbon dioxide to bicarbonate and protons. These isoforms are highly overexpressed in many types of cancer, where they contribute to the acidification of the tumor environment, promotin...