In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with Human Carbonic Anhydrase IX and XII Inhibition

• मुख्य लेखकों: Giosuè Costa (लेखक), Annalisa Maruca (लेखक), Roberta Rocca (लेखक), Francesca Alessandra Ambrosio (लेखक), Emanuela Berrino (लेखक), Fabrizio Carta (लेखक), Francesco Mesiti (लेखक), Alessandro Salatino (लेखक), Delia Lanzillotta (लेखक), Francesco Trapasso (लेखक), Anna Artese (लेखक), Stefano Alcaro (लेखक), Claudiu T. Supuran (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The tumor-associated isoenzymes <i>h</i>CA IX and <i>h</i>CA XII catalyze the hydration of carbon dioxide to bicarbonate and protons. These isoforms are highly overexpressed in many types of cancer, where they contribute to the acidification of the tumor environment, promotin...