In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with Human Carbonic Anhydrase IX and XII Inhibition

• Үндсэн зохиолчид: Giosuè Costa (Зохиогч), Annalisa Maruca (Зохиогч), Roberta Rocca (Зохиогч), Francesca Alessandra Ambrosio (Зохиогч), Emanuela Berrino (Зохиогч), Fabrizio Carta (Зохиогч), Francesco Mesiti (Зохиогч), Alessandro Salatino (Зохиогч), Delia Lanzillotta (Зохиогч), Francesco Trapasso (Зохиогч), Anna Artese (Зохиогч), Stefano Alcaro (Зохиогч), Claudiu T. Supuran (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2020-08-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The tumor-associated isoenzymes <i>h</i>CA IX and <i>h</i>CA XII catalyze the hydration of carbon dioxide to bicarbonate and protons. These isoforms are highly overexpressed in many types of cancer, where they contribute to the acidification of the tumor environment, promotin...