SPSB1‐mediated inhibition of TGF‐β receptor‐II impairs myogenesis in inflammation

• Principais autores: Yi Li (Autor), Niklas Dörmann (Autor), Björn Brinschwitz (Autor), Melanie Kny (Autor), Elisa Martin (Autor), Kirsten Bartels (Autor), Ning Li (Autor), Priyanka Voori Giri (Autor), Stefan Schwanz (Autor), Michael Boschmann (Autor), Susanne Hille (Autor), Britta Fielitz (Autor), Tobias Wollersheim (Autor), Julius Grunow (Autor), Stephan B. Felix (Autor), Steffen Weber‐Carstens (Autor), Friedrich C. Luft (Autor), Oliver J. Müller (Autor), Jens Fielitz (Autor)
• Formato: Livro
• Publicado em: Wiley, 2023-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Sepsis‐induced intensive care unit‐acquired weakness (ICUAW) features profound muscle atrophy and attenuated muscle regeneration related to malfunctioning satellite cells. Transforming growth factor beta (TGF‐β) is involved in both processes. We uncovered an increased expression...