Computational models for predicting drug transport mediated by P-glycoprotein

• Váldodahkkit: Erić Slavica (Dahkki), Kalinić Marko (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2015-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

P-glycoprotein (Pgp) is a transmembrane transporter which can, by transporting structurally diverse compounds, influence the absorption, distribution and efficacy of a number of drugs. Pgp overexpression in cells is a major contributing factor to the development of drug resistance. For these reasons...