Imaging Features of Non-Alcoholic Fatty Liver Disease in Children and Adolescents

Non-invasive diagnosis and quantification of liver steatosis is important to overcome limits of liver biopsy, in order to follow up patients during their therapy and to establish a reference standard that can be used in clinical trials and longitudinal studies. Imaging offers several methods in this...

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Main Authors: Michele Di Martino (Author), Kameliya Koryukova (Author), Mario Bezzi (Author), Carlo Catalano (Author)
Format: Book
Published: MDPI AG, 2017-08-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Michele Di Martino  |e author 
700 1 0 |a Kameliya Koryukova  |e author 
700 1 0 |a Mario Bezzi  |e author 
700 1 0 |a Carlo Catalano  |e author 
245 0 0 |a Imaging Features of Non-Alcoholic Fatty Liver Disease in Children and Adolescents 
260 |b MDPI AG,   |c 2017-08-01T00:00:00Z. 
500 |a 2227-9067 
500 |a 10.3390/children4080073 
520 |a Non-invasive diagnosis and quantification of liver steatosis is important to overcome limits of liver biopsy, in order to follow up patients during their therapy and to establish a reference standard that can be used in clinical trials and longitudinal studies. Imaging offers several methods in this setting: ultrasound, which is the cheapest technique and easy to perform; magnetic resonance spectroscopy (MRS), which reflects the real content of triglycerides in a specific volume; and proton density fat fraction (PDFF) magnetic resonance, which is a simple method that reflects the distribution of the fat in the whole liver. Other techniques include ultrasound elastography (EUS) and magnetic resonance elastrography (MRE), which can evaluate the progression of non-alcoholic fatty liver disease (NAFLD) into non-alcoholic steato-hepatitis (NASH) and cirrhosis, by quantifying liver fibrosis. 
546 |a EN 
690 |a NAFLD 
690 |a ultrasound 
690 |a proton density magnetic resonance 
690 |a magnetic resonance spectroscopy 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Children, Vol 4, Iss 8, p 73 (2017) 
787 0 |n https://www.mdpi.com/2227-9067/4/8/73 
787 0 |n https://doaj.org/toc/2227-9067 
856 4 1 |u https://doaj.org/article/4f80b30abd254c828c7b6b48ddd2580f  |z Connect to this object online.