NbX: Machine Learning-Guided Re-Ranking of Nanobody-Antigen Binding Poses

• Main Authors: Chunlai Tam (Author), Ashutosh Kumar (Author), Kam Y. J. Zhang (Author)
• Format: Bog
• Udgivet: MDPI AG, 2021-09-01T00:00:00Z.
• Fag: article
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Modeling the binding pose of an antibody is a prerequisite to structure-based affinity maturation and design. Without knowing a reliable binding pose, the subsequent structural simulation is largely futile. In this study, we have developed a method of machine learning-guided re-ranking of antigen bi...