Compassionate use of a novel β-lactam enhancer-based investigational antibiotic cefepime/zidebactam (WCK 5222) for the treatment of extensively-drug-resistant NDM-expressing Pseudomonas aeruginosa infection in an intra-abdominal infection-induced sepsis patient: a case report

• Main Authors: Dilip Dubey (Author), Manish Roy (Author), Tajamul H. Shah (Author), Noor Bano (Author), Vidushi Kulshrestha (Author), Sandeep Mitra (Author), Pushpender Sangwan (Author), Madhulika Dubey (Author), Ali Imran (Author), Bhawna Jain (Author), Aravind Velmurugan (Author), Yamuna Devi Bakthavatchalam (Author), Balaji Veeraraghavan (Author)
• Format: Book
• Published: BMC, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Infections in critically-ill patients caused by extensively-drug-resistant (XDR)-Pseudomonas aeruginosa are challenging to manage due to paucity of effective treatment options. Cefepime/zidebactam, which is currently in global Phase 3 clinical development (Clinical Trials Identifier: NCT049...