Immune disease variants modulate gene expression in regulatory CD4+ T cells

• Main Authors: Lara Bossini-Castillo (Author), Dafni A. Glinos (Author), Natalia Kunowska (Author), Gosia Golda (Author), Abigail A. Lamikanra (Author), Michaela Spitzer (Author), Blagoje Soskic (Author), Eddie Cano-Gamez (Author), Deborah J. Smyth (Author), Claire Cattermole (Author), Kaur Alasoo (Author), Alice Mann (Author), Kousik Kundu (Author), Anna Lorenc (Author), Nicole Soranzo (Author), Ian Dunham (Author), David J. Roberts (Author), Gosia Trynka (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Identifying cellular functions dysregulated by disease-associated variants could implicate novel pathways for drug targeting or modulation in cell therapies. However, follow-up studies can be challenging if disease-relevant cell types are difficult to sample. Variants associated with immune...