Combination therapy with rituximab and cyclophosphamide in the treatment of anti-neutrophil cytoplasmic antibodies (ANCA) positive pulmonary hemorrhage: case report

<p>Abstract</p> <p>Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with pulmonary hemorrhage is rare in childhood. Standard treatment includes corticosteroids and cyclophosphamide (CYC), which is associated with a high level of toxicity. We report a white fe...

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Bibliographic Details
Main Authors: Lehman Thomas JA (Author), Baird Emily M (Author), Worgall Stefan (Author)
Format: Book
Published: BMC, 2011-10-01T00:00:00Z.
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Summary:<p>Abstract</p> <p>Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with pulmonary hemorrhage is rare in childhood. Standard treatment includes corticosteroids and cyclophosphamide (CYC), which is associated with a high level of toxicity. We report a white female with ANCA positive pulmonary hemorrhage who was treated with cyclophosphamide (CYC) and rituximab (RTX) combination therapy.</p>
Item Description:10.1186/1546-0096-9-33
1546-0096