PINK1 protects against dendritic cell dysfunction during sepsis through the regulation of mitochondrial quality control

Abstract Background Dendritic cell (DC) dysfunction plays a central role in sepsis-induced immunosuppression. Recent research has indicated that collective mitochondrial fragmentation contributes to the dysfunction of immune cells observed during sepsis. PTEN-induced putative kinase 1 (PINK1) has be...

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Main Authors: You Wu (Author), Longwang Chen (Author), Zhimin Qiu (Author), Xijing Zhang (Author), Guangju Zhao (Author), Zhongqiu Lu (Author)
Format: Book
Published: BMC, 2023-02-01T00:00:00Z.
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