Interaction and potential mechanisms between atorvastatin and voriconazole, agents used to treat dyslipidemia and fungal infections

• Main Authors: Tianrong Xun (Author), Yan Rong (Author), Bin Lv (Author), Jinfei Tian (Author), Qing Zhang (Author), Xixiao Yang (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Purpose: Voriconazole (VOR) is combined with atorvastatin (ATO) to treat fungal infections in patients with dyslipidemia in clinical practice. However, the pharmacokinetic interactions and potential mechanisms between them are unknown. Therefore, this study aimed to investigate the pharmacokinetic i...