Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis

• Main Authors: Qingjuan Liu (Author), Yunxia Du (Author), Kejun Li (Author), Wei Zhang (Author), Xiaojuan Feng (Author), Jun Hao (Author), Hongbo Li (Author), Shuxia Liu (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this study was to investigate the role of oncostatin M (OSM) in tubulointerstitial lesion (TIL) in lupus nephritis (LN). We found that OSM was highly expressed in the renal tissue of LN mice. OSM is one of the interleukin-6 cytokine family members. In order to clarify the role and mec...