Nrf2 Mitigates RANKL and M-CSF Induced Osteoclast Differentiation via ROS-Dependent Mechanisms

• Main Authors: Yang Yang (Author), Zhiyuan Liu (Author), Jinzhi Wu (Author), Simeng Bao (Author), Yanshuai Wang (Author), Jiliang Li (Author), Tao Song (Author), Yongxin Sun (Author), Jingbo Pi (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nuclear factor-erythroid 2-related factor 2 (Nrf2) has been shown to be a negative regulator of osteoclast differentiation, but the precise mechanisms have not yet been established. We examined the precise roles of Nrf2 in regulating antioxidants and reactive oxygen species (ROS) levels, especially...