Oxidative Stress-Induced Misfolding and Inclusion Formation of Nrf2 and Keap1
Cells that experience high levels of oxidative stress respond by inducing antioxidant proteins through activation of the protein transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2). Nrf2 is negatively regulated by the E3 ubiquitin ligase Kelch-like ECH-associated protein 1 (Keap1...
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Main Authors: | Vy Ngo (Author), Nadun C. Karunatilleke (Author), Anne Brickenden (Author), Wing-Yiu Choy (Author), Martin L. Duennwald (Author) |
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Format: | Book |
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MDPI AG,
2022-01-01T00:00:00Z.
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