Functional testing of a human PBX3 variant in zebrafish reveals a potential modifier role in congenital heart defects
Whole-genome and exome sequencing efforts are increasingly identifying candidate genetic variants associated with human disease. However, predicting and testing the pathogenicity of a genetic variant remains challenging. Genome editing allows for the rigorous functional testing of human genetic vari...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2018-10-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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