Veratramine ameliorates pain symptoms in rats with diabetic peripheral neuropathy by inhibiting activation of the SIGMAR1-NMDAR pathway

• Main Authors: Yu Zhang (Author), Guangyao Ye (Author), Yuebo Chen (Author), Chaoxu Sheng (Author), Jianlin Wang (Author), Lingsi Kong (Author), Liyong Yuan (Author), Chunyan Lin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Veratramine may have a potential therapeutic effect for diabetic peripheral neuropathy (DPN).Objective To evaluate whether veratramine ameliorates neuropathic pain in a rat diabetic model.Materials and methods Sprague-Dawley rats were used for a diabetic model induced by a streptozotocin + h...