Myocyte-specific overexpressing HDAC4 promotes myocardial ischemia/reperfusion injury

• Main Authors: Ling Zhang (Author), Hao Wang (Author), Yu Zhao (Author), Jianguo Wang (Author), Patrycja M. Dubielecka (Author), Shougang Zhuang (Author), Gangjian Qin (Author), Y Eugene Chin (Author), Race L. Kao (Author), Ting C. Zhao (Author)
• Format: Book
• Published: BMC, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Histone deacetylases (HDACs) play a critical role in modulating myocardial protection and cardiomyocyte survivals. However, Specific HDAC isoforms in mediating myocardial ischemia/reperfusion injury remain currently unknown. We used cardiomyocyte-specific overexpression of active...