Evaluation of microsatellite instability in routine examinations of surgical samples

Context: Approximately 20%-30% of colon cancer cases have a hereditary basis. The genetic defect may involve mismatch repair (MMR) genes, which results in microsatellite instability (MSI). MMR-deficient colorectal cancer may occur due to germline mutation (Lynch syndrome) or be a sporadic one. A tum...

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Main Authors: Pawel Wlaszczuk (Author), Aleksandra Kuzbinska (Author), Zuzanna Dobrosz (Author), Piotr Palen (Author), Krzysztof Pawlicki (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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