Proprotein convertase subtilisin/kexin type 9 deficiency in extrahepatic tissues: emerging considerations
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is primarily secreted by hepatocytes. PCSK9 is critical in liver low-density lipoprotein receptors (LDLRs) metabolism. In addition to its hepatocellular presence, PCSK9 has also been detected in cardiac, cerebral, islet, renal, adipose, and other...
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| Main Authors: | , , |
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| Format: | Book |
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Frontiers Media S.A.,
2024-07-01T00:00:00Z.
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