PI3K/AKT and STAT3 pathways mediate the neuroprotective effect of dasatinib from acute cerebral injury in endotoxemic mice

• Główni autorzy: Ammar Rasoul Mohammad (Autor), Ekhlas Sabah Hassan (Autor), Sahar Abdulrudha Majeed (Autor)
• Format: Książka
• Wydane: Wolters Kluwer Medknow Publications, 2024-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Background and purpose: Sepsis induces brain dysfunction and there is still a requirement for an unemployed viable restorative approach. This study aimed to investigate the role of dasatinib in the modulation of proinflammatory mediators, attenuating neuroinflammatory response, and it's signali...