Urinary Carnosinase-1 Excretion is Associated with Urinary Carnosine Depletion and Risk of Graft Failure in Kidney Transplant Recipients: Results of the TransplantLines Cohort Study

• Main Authors: Angelica Rodriguez-Niño (Author), Diego O. Pastene (Author), Adrian Post (Author), M. Yusof Said (Author), Antonio W. Gomes-Neto (Author), Lyanne M. Kieneker (Author), M. Rebecca Heiner-Fokkema (Author), Tuba Esatbeyoglu (Author), Gerald Rimbach (Author), Peter Schnuelle (Author), Benito A. Yard (Author), Stephan J. L. Bakker (Author)
• Format: Bog
• Udgivet: MDPI AG, 2021-07-01T00:00:00Z.
• Fag: article
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Carnosine affords protection against oxidative and carbonyl stress, yet high concentrations of the carnosinase-1 enzyme may limit this. We recently reported that high urinary carnosinase-1 is associated with kidney function decline and albuminuria in patients with chronic kidney disease. We prospect...