The microbiota-gut-brain axis: clinical applications in obesity and type 2 diabetes

Recent investigations highlight the importance of the gut microbiota and bacteria-derived metabolites as key components in obesity and metabolic health. The microbiota-gut-brain axis presents promising targets for future obesity treatments and prevention. However, the current state of evidence and e...

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Bibliographic Details
Main Authors: Brandy Moser (Author), Megan A. Milligan (Author), Maria C. Dao (Author)
Format: Book
Published: Permanyer, 2022-01-01T00:00:00Z.
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Summary:Recent investigations highlight the importance of the gut microbiota and bacteria-derived metabolites as key components in obesity and metabolic health. The microbiota-gut-brain axis presents promising targets for future obesity treatments and prevention. However, the current state of evidence and existing clinical applications of the microbiota-gut-brain axis have yet to be summarized in a thorough review. Therefore, we sought to examine current evidence on the effect of lifestyle, dietary, pharmacological, and surgical interventions on the microbiota-gut-brain axis. In addition, this review highlights potential next steps in research toward characterizing the role of the microbiota-gut-brain axis in metabolic health, along with possible interventions to address obesity.
Item Description:10.24875/RIC.22000197
0034-8376
2564-8896