Evaluation of serum anti-pertussis toxin IgA antibodies for the diagnosis of Bordetella pertussis infection in young children

• Main Authors: Zhiyun Chen (Author), Xiaoguai Liu (Author), Yuxiao Zhang (Author), Xiaokang Peng (Author), Nan Zhang (Author), Ning Chen (Author), Yarong Li (Author), Qiushui He (Author)
• Format: Book
• Published: Elsevier, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The determination of serum anti-pertussis toxin (PT) IgG antibodies is recommended for the diagnosis and surveillance of pertussis. However, the diagnostic power of anti-PT IgG can be hampered by possible interference from previous vaccinations. We aim to assess if anti-PT IgA antibodies...