17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line

Aims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory actions of the steroid hormones, the purpose of this stu...

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Bibliographic Details
Main Authors: Margarida Castro-Caldas (Author), Carlos B. Duarte (Author), Arsélio P. Carvalho (Author), M. Celeste Lopes (Author)
Format: Book
Published: Hindawi Limited, 2001-01-01T00:00:00Z.
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Summary:Aims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory actions of the steroid hormones, the purpose of this study was to investigate the effects of the female sex steroid hormone, 17β-estradiol (E2β), on the synthesis and secretion of ANXA1 in the human CCRF-CEM acute lymphoblastic leukemia cell line.
Item Description:0962-9351
1466-1861
10.1080/09629350120093713