Successful treatment of refractory hyperferritinemic syndromes with canakinumab: a report of two cases

• Main Authors: Riccardo Papa (Author), Valentina Natoli (Author), Roberta Caorsi (Author), Francesca Minoia (Author), Marco Gattorno (Author), Angelo Ravelli (Author)
• Format: Book
• Published: BMC, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hyperferritinemic syndromes are systemic inflammatory disorders characterized by a dysfunctional immune response, which leads to excessive activation of the monocyte-macrophage system with hypercytokinemia and may pursue a rapidly fatal course. Case presentation We describe two p...