Study protocol: NeoCLEAR: Neonatal Champagne Lumbar punctures Every time - An RCT: a multicentre, randomised controlled 2 × 2 factorial trial to investigate techniques to increase lumbar puncture success

• Main Authors: Andrew S. J. Marshall (Author), Manish Sadarangani (Author), Alexandra Scrivens (Author), Rachel Williams (Author), Jean Yong (Author), Ursula Bowler (Author), Louise Linsell (Author), Virginia Chiocchia (Author), Jennifer L. Bell (Author), Caz Stokes (Author), Patricia Santhanadass (Author), Eleri Adams (Author), Edmund Juszczak (Author), Charles C. Roehr (Author), on behalf of the 'The NeoCLEAR Collaborative Group' (Author)
• Format: Book
• Published: BMC, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The neonatal period carries the highest risk of bacterial meningitis (~ 1 in 5000 births), bearing high mortality (~ 10%) and morbidity (20-50%) rates. Lumbar puncture (LP) remains essential to the diagnosis of meningitis. Though LP is a common procedure in neonates, success rate...