Sperm-borne microRNA-34c regulates maternal mRNA degradation and preimplantation embryonic development in mice

• Main Authors: Long Cui (Author), Li Fang (Author), Lili Zhuang (Author), Biwei Shi (Author), Chao-Po Lin (Author), Yinghui Ye (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Studies have shown that sperm-borne microRNAs (miRNAs) are involved in mammalian preimplantation embryonic development. In humans, spermatozoan miR-34c levels are correlated with in vitro fertilization outcomes, such as embryo quality and the clinical pregnancy and live birth rat...