Novel human monoclonal antibodies specific to the alternatively spliced domain D of Tenascin C efficiently target tumors in vivo

• Päätekijät: Lisa Nadal (Tekijä), Riccardo Corbellari (Tekijä), Alessandra Villa (Tekijä), Tobias Weiss (Tekijä), Michael Weller (Tekijä), Dario Neri (Tekijä), Roberto De Luca (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Antibody-based delivery of bioactive molecules represents a promising strategy for the improvement of cancer immunotherapy. Here, we describe the generation and characterization of R6N, a novel fully human antibody specific to the alternatively spliced domain D of Tenascin C, which is highly express...