Novel human monoclonal antibodies specific to the alternatively spliced domain D of Tenascin C efficiently target tumors in vivo

• Auteurs principaux: Lisa Nadal (Auteur), Riccardo Corbellari (Auteur), Alessandra Villa (Auteur), Tobias Weiss (Auteur), Michael Weller (Auteur), Dario Neri (Auteur), Roberto De Luca (Auteur)
• Format: Livre
• Publié: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Antibody-based delivery of bioactive molecules represents a promising strategy for the improvement of cancer immunotherapy. Here, we describe the generation and characterization of R6N, a novel fully human antibody specific to the alternatively spliced domain D of Tenascin C, which is highly express...