Novel human monoclonal antibodies specific to the alternatively spliced domain D of Tenascin C efficiently target tumors in vivo

• मुख्य लेखकों: Lisa Nadal (लेखक), Riccardo Corbellari (लेखक), Alessandra Villa (लेखक), Tobias Weiss (लेखक), Michael Weller (लेखक), Dario Neri (लेखक), Roberto De Luca (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Antibody-based delivery of bioactive molecules represents a promising strategy for the improvement of cancer immunotherapy. Here, we describe the generation and characterization of R6N, a novel fully human antibody specific to the alternatively spliced domain D of Tenascin C, which is highly express...