Novel human monoclonal antibodies specific to the alternatively spliced domain D of Tenascin C efficiently target tumors in vivo

• 主要な著者: Lisa Nadal (著者), Riccardo Corbellari (著者), Alessandra Villa (著者), Tobias Weiss (著者), Michael Weller (著者), Dario Neri (著者), Roberto De Luca (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Antibody-based delivery of bioactive molecules represents a promising strategy for the improvement of cancer immunotherapy. Here, we describe the generation and characterization of R6N, a novel fully human antibody specific to the alternatively spliced domain D of Tenascin C, which is highly express...