Novel human monoclonal antibodies specific to the alternatively spliced domain D of Tenascin C efficiently target tumors in vivo

• Главные авторы: Lisa Nadal (Автор), Riccardo Corbellari (Автор), Alessandra Villa (Автор), Tobias Weiss (Автор), Michael Weller (Автор), Dario Neri (Автор), Roberto De Luca (Автор)
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• Опубликовано: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Предметы: article
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Antibody-based delivery of bioactive molecules represents a promising strategy for the improvement of cancer immunotherapy. Here, we describe the generation and characterization of R6N, a novel fully human antibody specific to the alternatively spliced domain D of Tenascin C, which is highly express...