Novel human monoclonal antibodies specific to the alternatively spliced domain D of Tenascin C efficiently target tumors in vivo

• Váldodahkkit: Lisa Nadal (Dahkki), Riccardo Corbellari (Dahkki), Alessandra Villa (Dahkki), Tobias Weiss (Dahkki), Michael Weller (Dahkki), Dario Neri (Dahkki), Roberto De Luca (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Antibody-based delivery of bioactive molecules represents a promising strategy for the improvement of cancer immunotherapy. Here, we describe the generation and characterization of R6N, a novel fully human antibody specific to the alternatively spliced domain D of Tenascin C, which is highly express...