Novel human monoclonal antibodies specific to the alternatively spliced domain D of Tenascin C efficiently target tumors in vivo

• Asıl Yazarlar: Lisa Nadal (Yazar), Riccardo Corbellari (Yazar), Alessandra Villa (Yazar), Tobias Weiss (Yazar), Michael Weller (Yazar), Dario Neri (Yazar), Roberto De Luca (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Antibody-based delivery of bioactive molecules represents a promising strategy for the improvement of cancer immunotherapy. Here, we describe the generation and characterization of R6N, a novel fully human antibody specific to the alternatively spliced domain D of Tenascin C, which is highly express...