Maternal immunoglobulins are distributed in the offspring's brain to support the maintenance of cortical interneurons in the postnatal period

• Main Authors: Keiko Morimoto (Author), Rikuo Takahashi (Author), Goro Takahashi (Author), Michio Miyajima (Author), Kazunori Nakajima (Author)
• Formato: Livro
• Publicado em: BMC, 2024-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract It is known that maternal immunoglobulins (Igs) are transferred to the offspring across the placenta. However, receiving maternal Igs, especially before the blood-brain barrier (BBB) is formed in the offspring's brain, carries the risk of transferring some brain-reactive Igs. It is thu...