Synthesis, Formulation and Characterization of Immunotherapeutic Glycosylated Dendrimer/cGAMP Complexes for CD206 Targeted Delivery to M2 Macrophages in Cold Tumors

• Main Authors: Marija Petrovic (Author), Alexandre Porcello (Author), Stoyan Tankov (Author), Oliwia Majchrzak (Author), Martin Kiening (Author), Annick Clara Laingoniaina (Author), Tayeb Jbilou (Author), Paul R. Walker (Author), Gerrit Borchard (Author), Olivier Jordan (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Anti-tumor responses can be achieved via the stimulation of the immune system, a therapeutic approach called cancer immunotherapy. Many solid tumor types are characterized by the presence of immune-suppressive tumor-associated macrophage (TAMs) cells within the tumor microenvironment (TME). Moreover...