Population Pharmacokinetics of Polymyxin B in Obese Patients for Resistant Gram-Negative Infections

• Κύριοι συγγραφείς: Peile Wang (Συγγραφέας), Qiwen Zhang (Συγγραφέας), Min Feng (Συγγραφέας), Tongwen Sun (Συγγραφέας), Jing Yang (Συγγραφέας), Xiaojian Zhang (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Polymyxin B is an effective but potentially nephrotoxic antibiotic that is commonly used to treat resistant Gram-negative infections. As a weight-based dosing drug, obese patients may be at a high risk of nephrotoxicity. However, the pharmacokinetics and dosing recommendations for this population ar...