Population pharmacokinetic study of pemetrexed in chinese primary advanced non-small cell lung carcinoma patients

• Main Authors: Peng Cao (Author), Wei Guo (Author), Jun Wang (Author), Sanlan Wu (Author), Yifei Huang (Author), Yang Wang (Author), Yani Liu (Author), Yu Zhang (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Fag: article
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The purposes of this study were to identify physiological and genetic factors that contributed to variability of pemetrexed (PEM) exposure and to optimize the dosing regimens for Chinese non-small cell lung carcinoma patients. A prospective population pharmacokinetics (PPK) research was performed in...