Population pharmacokinetic study of pemetrexed in chinese primary advanced non-small cell lung carcinoma patients

• Hauptverfasser: Peng Cao (Verfasst von), Wei Guo (Verfasst von), Jun Wang (Verfasst von), Sanlan Wu (Verfasst von), Yifei Huang (Verfasst von), Yang Wang (Verfasst von), Yani Liu (Verfasst von), Yu Zhang (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The purposes of this study were to identify physiological and genetic factors that contributed to variability of pemetrexed (PEM) exposure and to optimize the dosing regimens for Chinese non-small cell lung carcinoma patients. A prospective population pharmacokinetics (PPK) research was performed in...