Population pharmacokinetic study of pemetrexed in chinese primary advanced non-small cell lung carcinoma patients

• Κύριοι συγγραφείς: Peng Cao (Συγγραφέας), Wei Guo (Συγγραφέας), Jun Wang (Συγγραφέας), Sanlan Wu (Συγγραφέας), Yifei Huang (Συγγραφέας), Yang Wang (Συγγραφέας), Yani Liu (Συγγραφέας), Yu Zhang (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

The purposes of this study were to identify physiological and genetic factors that contributed to variability of pemetrexed (PEM) exposure and to optimize the dosing regimens for Chinese non-small cell lung carcinoma patients. A prospective population pharmacokinetics (PPK) research was performed in...