Population pharmacokinetic study of pemetrexed in chinese primary advanced non-small cell lung carcinoma patients

• Главные авторы: Peng Cao (Автор), Wei Guo (Автор), Jun Wang (Автор), Sanlan Wu (Автор), Yifei Huang (Автор), Yang Wang (Автор), Yani Liu (Автор), Yu Zhang (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Предметы: article
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The purposes of this study were to identify physiological and genetic factors that contributed to variability of pemetrexed (PEM) exposure and to optimize the dosing regimens for Chinese non-small cell lung carcinoma patients. A prospective population pharmacokinetics (PPK) research was performed in...