Population pharmacokinetic study of pemetrexed in chinese primary advanced non-small cell lung carcinoma patients

• Автори: Peng Cao (Автор), Wei Guo (Автор), Jun Wang (Автор), Sanlan Wu (Автор), Yifei Huang (Автор), Yang Wang (Автор), Yani Liu (Автор), Yu Zhang (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

The purposes of this study were to identify physiological and genetic factors that contributed to variability of pemetrexed (PEM) exposure and to optimize the dosing regimens for Chinese non-small cell lung carcinoma patients. A prospective population pharmacokinetics (PPK) research was performed in...