Gemcitabine-Vitamin E Prodrug-Loaded Micelles for Pancreatic Cancer Therapy

• Main Authors: Miguel Pereira-Silva (Author), Darío Miranda-Pastoriza (Author), Luis Diaz-Gomez (Author), Eddy Sotelo (Author), Ana Cláudia Paiva-Santos (Author), Francisco Veiga (Author), Angel Concheiro (Author), Carmen Alvarez-Lorenzo (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pancreatic cancer (PC) is an aggressive cancer subtype presenting unmet clinical challenges. Conventional chemotherapy, which includes antimetabolite gemcitabine (GEM), is seriously undermined by a short half-life, its lack of targeting ability, and systemic toxicity. GEM incorporation in self-assem...