The Ins and Outs of Messenger RNA Electroporation for Physical Gene Delivery in Immune Cell-Based Therapy

• Автори: Diana Campillo-Davo (Автор), Maxime De Laere (Автор), Gils Roex (Автор), Maarten Versteven (Автор), Donovan Flumens (Автор), Zwi N. Berneman (Автор), Viggo F. I. Van Tendeloo (Автор), Sébastien Anguille (Автор), Eva Lion (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2021-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Messenger RNA (mRNA) electroporation is a powerful tool for transient genetic modification of cells. This non-viral method of genetic engineering has been widely used in immunotherapy. Electroporation allows fine-tuning of transfection protocols for each cell type as well as introduction of multiple...