Towards the Development of a Female Animal Model of T1DM Using Hyaluronic Acid Nanocoated Cell Transplantation: Refinements and Considerations for Future Protocols

• Auteurs principaux: Fernanda Zamboni (Auteur), Ibrahim F. Cengiz (Auteur), Ana M. Barbosa (Auteur), Antonio G. Castro (Auteur), Rui L. Reis (Auteur), Joaquim M. Oliveira (Auteur), Maurice N. Collins (Auteur)
• Format: Livre
• Publié: MDPI AG, 2021-11-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Female mice (Black 6 strain) (C57BL/6) aged 6 weeks were subject to low dose streptozotocin (STZ) treatment for five consecutive days to mimic type 1 diabetes mellitus (T1DM) with insulitis. At two weeks after STZ injections, evaluation of the elevated glucose levels was used to confirm diabetes. Th...