Induced Expression of kir6.2 in A1 Astrocytes Propagates Inflammatory Neurodegeneration via Drp1-dependent Mitochondrial Fission

• المؤلفون الرئيسيون: Nanshan Song (مؤلف), Hong Zhu (مؤلف), Rong Xu (مؤلف), Jiaqi Liu (مؤلف), Yinquan Fang (مؤلف), Jing Zhang (مؤلف), Jianhua Ding (مؤلف), Gang Hu (مؤلف), Ming Lu (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Glia-mediated inflammatory processes are crucial in the pathogenesis of Parkinson's disease (PD). As the most abundant cells of the brain and active participants in neuroinflammatory responses, astrocytes largely propagate inflammatory signals and amplify neuronal loss. Hence, intensive control...