Induced Expression of kir6.2 in A1 Astrocytes Propagates Inflammatory Neurodegeneration via Drp1-dependent Mitochondrial Fission

• Κύριοι συγγραφείς: Nanshan Song (Συγγραφέας), Hong Zhu (Συγγραφέας), Rong Xu (Συγγραφέας), Jiaqi Liu (Συγγραφέας), Yinquan Fang (Συγγραφέας), Jing Zhang (Συγγραφέας), Jianhua Ding (Συγγραφέας), Gang Hu (Συγγραφέας), Ming Lu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Glia-mediated inflammatory processes are crucial in the pathogenesis of Parkinson's disease (PD). As the most abundant cells of the brain and active participants in neuroinflammatory responses, astrocytes largely propagate inflammatory signals and amplify neuronal loss. Hence, intensive control...