Induced Expression of kir6.2 in A1 Astrocytes Propagates Inflammatory Neurodegeneration via Drp1-dependent Mitochondrial Fission

• Үндсэн зохиолчид: Nanshan Song (Зохиогч), Hong Zhu (Зохиогч), Rong Xu (Зохиогч), Jiaqi Liu (Зохиогч), Yinquan Fang (Зохиогч), Jing Zhang (Зохиогч), Jianhua Ding (Зохиогч), Gang Hu (Зохиогч), Ming Lu (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Glia-mediated inflammatory processes are crucial in the pathogenesis of Parkinson's disease (PD). As the most abundant cells of the brain and active participants in neuroinflammatory responses, astrocytes largely propagate inflammatory signals and amplify neuronal loss. Hence, intensive control...