Induced Expression of kir6.2 in A1 Astrocytes Propagates Inflammatory Neurodegeneration via Drp1-dependent Mitochondrial Fission

• Главные авторы: Nanshan Song (Автор), Hong Zhu (Автор), Rong Xu (Автор), Jiaqi Liu (Автор), Yinquan Fang (Автор), Jing Zhang (Автор), Jianhua Ding (Автор), Gang Hu (Автор), Ming Lu (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Предметы: article
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Glia-mediated inflammatory processes are crucial in the pathogenesis of Parkinson's disease (PD). As the most abundant cells of the brain and active participants in neuroinflammatory responses, astrocytes largely propagate inflammatory signals and amplify neuronal loss. Hence, intensive control...